The OLR1 Antibody (CAB12060) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the OLR1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cardiovascular disease, atherosclerosis, and metabolic disorders.OLR1, also known as oxidized low-density lipoprotein receptor 1, plays a crucial role in lipid uptake and transport, as well as in inflammatory responses triggered by oxidized lipids.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
OLR1 Antibody
SKU:
CAB12060
Size:
20μL, 100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LOX1, LOXIN, SLOX1, CLEC8A, SCARE1, OLR1
Positive Sample:
Mouse lung
Cellular Localization:
Cell Membrane, Lipid-Anchor, Membrane Raft, Secreted, Single-Pass Type Ii Membrane Protein.
Calculated MW:
31kDa
Observed MW:
31kDa
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
4973
RRID
AB_2758967
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using OLR1 Rabbit pAb (CAB12060) at 1:1000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
