The OR4X1 Monoclonal Antibody (PACO06711) is specifically designed for research involving OR4X1, a member of the olfactory receptor (OR) family of G-protein coupled receptors (GPCRs). This antibody, generated in mice, is highly specific and suitable for use in various applications including immunofluorescence and flow cytometry. It selectively binds to the OR4X1 receptor, enabling its detection and analysis in different cell types and tissues, making it ideal for studies in sensory biology and olfaction research.
OR4X1 is a key player in the olfactory system, responsible for detecting specific odorants and transmitting signals to the brain for odor perception. Its unique function in olfaction makes it an important target for research in understanding how the sense of smell works and how different odors are detected and processed. Investigating the role of OR4X1 can provide insights into neurological disorders related to olfaction and potential therapeutic targets for olfactory dysfunction.
Antibody Name:
OR4X1 Antibody (PACO06711)
Antibody SKU:
PACO06711
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:20000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human Olfactory receptor 4X1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of various cells using Olfactory receptor 4X1 Polyclonal Antibody.
Western Blot analysis of COLO205 cells using Olfactory receptor 4X1 Polyclonal Antibody.
OR4X1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 11p11.2Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015]
