The OSTM1 Antibody (CAB11685) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the OSTM1 protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent tool for studies in bone biology and genetic disorders.OSTM1 plays a crucial role in bone homeostasis by facilitating the resorption of bone tissue.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
OSTM1 Antibody
SKU:
CAB11685
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GL, GIPN, OPTB5, HSPC019, OSTM1
Positive Sample:
HeLa, 293T, A-549, Raji, B cells, Mouse brain, Mouse kidney
Cellular Localization:
Lysosome Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
37kDa
Observed MW:
30-37kDa
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
Purification Method
Affinity purification
Gene ID
28962
RRID
AB_2758687
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using OSTM1 Rabbit pAb (CAB11685) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
