The KO validated OXCT1 Polyclonal Antibody (CAB8139) is a specialized research tool for studying OXCT1, a key enzyme involved in ketone body metabolism. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards OXCT1 in human samples, making it an ideal choice for Western blot applications.OXCT1 is essential for ketone body utilization in cells and is implicated in various metabolic disorders such as diabetes and obesity. By targeting OXCT1, researchers can gain insights into the role of ketone metabolism in these diseases, paving the way for potential therapeutic interventions.
The validation of this antibody for knockout (KO) samples ensures its reliability and accuracy in experimental studies. Whether investigating ketone metabolism, metabolic disorders, or related pathways, the KO validated OXCT1 Polyclonal Antibody is a valuable tool for enhancing your research in the field of metabolism and metabolic diseases.
Product Name:
[KO Validated] OXCT1 Rabbit Polyclonal Antibody
SKU:
CAB8139
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 261-520 of human OXCT1 (NP_000427.1).
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Purification Method:
Affinity purification
Gene ID:
5019
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using OXCT1 antibody (CAB8139) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
