The CD300A Polyclonal Antibody (PACO34008) is a crucial tool for researchers studying immune regulation and immune response modulation. This antibody, produced in rabbits, specifically targets the CD300A protein, a cell surface molecule known for its role in inhibiting immune responses.Validated for use in Western blot applications, this antibody is highly reactive with human samples, allowing for thorough detection and analysis of CD300A in various cell types. Its utility in immunology and cancer research makes it an essential component for studies involving diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
By understanding the activity of CD300A and its impact on immune homeostasis, researchers can develop targeted therapies that modulate immune function to combat a range of diseases. The CD300A Polyclonal Antibody is a valuable tool for unlocking the potential of immune regulation in the fight against these debilitating conditions.
Antibody Name:
P Antibody (PACO34008)
Antibody SKU:
PACO34008
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Rabies virus
Immunogen:
Recombinant Rabies virus Phosphoprotein protein (1-297AA)
Western blot. All lanes: P antibody at 2µg/ml. Lane 1: Rabies virus Phosphoprotein protein at 1µg. Lane 2: Rabies virus Phosphoprotein protein at 0.1µg. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 34, 32, 28, 26, 25 kDa. Observed band size: 34 kDa.
Background:
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-α and IFN-β signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body
Synonyms:
Phosphoprotein (Protein P) (Protein M1), P
UniProt Protein Function:
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body ().
