The CD300A Polyclonal Antibody (PACO34294) offered by AssayGenie is a valuable tool for researchers studying the cell surface molecule CD300A. This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in Western blot applications. By binding to the CD300A protein, this antibody enables scientists to detect and analyze CD300A expression in a variety of cell types.CD300A, also known as an immune inhibitory receptor, plays a crucial role in immune regulation by inhibiting immune responses. Understanding the function of CD300A is essential for research into immune-related diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
By studying CD300A, researchers can gain valuable insights into immune homeostasis and potentially develop new therapies targeting immune function.Overall, the CD300A Polyclonal Antibody (PACO34294) is a valuable tool for immunology and cancer research, offering researchers the ability to study the role of CD300A in immune regulation and its implications for various diseases.
Antibody Name:
P Antibody (PACO34294)
Antibody SKU:
PACO34294
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Hepatitis B virus genotype A2 subtype adw2
Immunogen:
Recombinant Hepatitis B virus genotype A2 subtype adw2 Protein P protein (349-692AA)
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
Synonyms:
Protein P [Includes: DNA-directed DNA polymerase (EC 2.7.7.7); RNA-directed DNA polymerase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4)], P
UniProt Protein Function:
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery ().
