The P2RY2 Antibody (CAB5779) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, displays high sensitivity and specificity in detecting P2Y Purinoceptor 2 protein in human samples, making it ideal for use in Western blot applications.P2Y Purinoceptor 2 is a G protein-coupled receptor involved in mediating cellular responses to extracellular nucleotides, such as ATP and ADP. Its activation plays a crucial role in diverse cellular functions, including neurotransmission, inflammation, and platelet aggregation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
P2RY2 Antibody
SKU:
CAB5779
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
P2U, HP2U, P2U1, P2UR, P2Y2, P2RU1, P2Y2R, P2RY2
Positive Sample:
Mouse skeletal muscle
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
42kDa
Observed MW:
51kDa
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
Purification Method
Affinity purification
Gene ID
5029
RRID
AB_2766534
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse skeletal muscle, using P2RY2 Rabbit pAb (CAB5779) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 30s.
