The PARG Monoclonal Antibody (CAB24811) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed through mouse hybridoma technology, exhibits high specificity and sensitivity in detecting PARG in various biological samples. Validated for use in immunofluorescence and immunoprecipitation assays, it allows for accurate visualization and analysis of PARG expression and localization in cells.PARG plays a crucial role in maintaining genomic stability and preventing DNA damage by catalyzing the hydrolysis of poly(ADP-ribose) chains.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
PARG Monoclonal Antibody
SKU:
CAB24811
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC63810
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
8505
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from PC-3 cells, using PARG Rabbit mAb (CAB24811) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
