The PDCD5 Polyclonal Antibody (CAB7298) is a valuable tool for researchers studying PDCD5, a protein involved in programmed cell death and apoptosis. This antibody, generated in rabbits, exhibits high specificity and sensitivity for PDCD5 in human samples, making it ideal for use in Western blot applications. By binding to the PDCD5 protein, this antibody enables the detection and analysis of PDCD5 expression in various cell types, facilitating investigations in areas such as cell signaling, cancer biology, and neurodegenerative diseases.PDCD5, also known as programmed cell death protein 5, plays a crucial role in regulating cell death pathways and maintaining cellular homeostasis.
Dysregulation of PDCD5 expression has been linked to various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions. Understanding the function of PDCD5 is essential for developing targeted therapies to manipulate cell death processes and treat these diseases effectively. Researchers can rely on the PDCD5 Polyclonal Antibody (CAB7298) to explore the intricate role of PDCD5 in different biological contexts and advance our knowledge of cell death mechanisms.
Product Name:
PDCD5 Rabbit Polyclonal Antibody
SKU:
CAB7298
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human PDCD5 (NP_004699.1).
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12
Purification Method:
Affinity purification
Gene ID:
9141
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDCD5 Antibody (CAB7298) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
