Anti-PDCD5 Antibody (CAB7298)

Antibody Name:	Anti-PDCD5 Antibody
Antibody SKU:	CAB7298
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human PDCD5 (NP_004699.1).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:	Human, Mouse, Rat
Positive Samples:	Mouse heart, Mouse testis, Rat heart

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human PDCD5 (NP_004699.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MADE ELEA LRRQ RLAE LQAK HGDP GDAA QQEA KHRE AEMR NSIL AQVL DQSA RARL SNLA LVKP EKTK AVEN YLIQ MARY GQLS EKVS EQGL IEIL KKVS QQTE KTTT VKFN RRKV MDSD EDDD Y
Gene ID:	9141
Uniprot:	O14737
Cellular Location:
Calculated MW:	14kDa
Observed MW:	14kDa

Synonyms:

PDCD5, TFAR19

Background:

This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12

UniProt Protein Function:	PDCD5: May function in the process of apoptosis. Belongs to the PDCD5 family.
UniProt Protein Details:	Protein type:Apoptosis Chromosomal Location of Human Ortholog: 19q13.11 Cellular Component: cytoplasm; nucleus Molecular Function:heparin binding; protein binding; DNA binding; beta-tubulin binding Biological Process: negative regulation of cell proliferation; positive regulation of apoptosis; positive regulation of caspase activity
NCBI Summary:	This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]
UniProt Code:	O14737
NCBI GenInfo Identifier:	6226219
NCBI Gene ID:	9141
NCBI Accession:	O14737.3
UniProt Related Accession:	O14737
Molecular Weight:
NCBI Full Name:	Programmed cell death protein 5
NCBI Synonym Full Names:	programmed cell death 5
NCBI Official Symbol:	PDCD5
NCBI Official Synonym Symbols:	TFAR19
NCBI Protein Information:	programmed cell death protein 5
UniProt Protein Name:	Programmed cell death protein 5
UniProt Synonym Protein Names:	TF-1 cell apoptosis-related protein 19; Protein TFAR19
Protein Family:	Programmed cell death protein
UniProt Gene Name:	PDCD5
UniProt Entry Name:	PDCD5_HUMAN

	Western blot analysis of extracts of various cell lines, using PDCD5 Antibody (CAB7298) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s.
	Immunofluorescence analysis of L929 cells using PDCD5 Rabbit pAb (CAB7298) at dilution of 1:100. Blue: DAPI for nuclear staining.

Antibodies

PDCD5 Antibody (PACO11128)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)