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PE Anti-Human CD20 Antibody [2H7] (AGEL2393)

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SKU AGEL2393
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, κ
Clone 2H7
Conjugation PE
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Description

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PE Anti-Human CD20 Antibody [2H7]

The PE Anti-Human CD20 Antibody (2H7) available at Assaygenie is a powerful tool for researchers studying CD20, a cell surface protein commonly found on B cells. This antibody, labeled with phycoerythrin (PE), is specifically designed for flow cytometry applications, enabling accurate and sensitive detection of CD20 expression in human samples.CD20 is a well-known biomarker for B-cell identification and is frequently targeted in therapies for B-cell malignancies like non-Hodgkin's lymphoma and chronic lymphocytic leukemia. The PE Anti-Human CD20 Antibody (2H7) is highly specific and reliable for distinguishing CD20-positive cells in flow cytometry experiments, making it an essential reagent for immunology and oncology research.

By facilitating the precise identification and quantification of CD20-expressing cells, this antibody plays a crucial role in understanding B-cell biology and developing targeted therapies for B-cell-related diseases. Its high reactivity and validation for use in flow cytometry applications make it a valuable asset for researchers investigating B-cell disorders and immunotherapy strategies.

Product Title:PE Anti-Human CD20 Antibody [2H7]
SKU:AGEL2393
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2H7
Synonyms:Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:PE Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

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