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PE Anti-Mouse CD107a Antibody [1D4B] (AGEL3287)

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SKU AGEL3287
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Applications ICFCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, k
Clone 1D4B
Conjugation PE
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Description

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PE Anti-Mouse CD107a Antibody [1D4B]

The PE Anti-Mouse CD107a Antibody (1D4B) from Assay Genie is a valuable tool for researchers studying immune responses in mice. This antibody is specifically designed to target CD107a, a cell surface marker involved in immune cell degranulation and cytotoxic activity. By binding to CD107a, this antibody allows for the detection and analysis of this important protein in mouse samples.CD107a, also known as LAMP-1, is a key player in the regulation of immune responses, particularly in the context of cytotoxic T cell and natural killer cell function. By targeting CD107a, researchers can gain insights into the mechanisms underlying immune cell activation and effector functions.

This antibody is ideal for use in flow cytometry and other immunological assays to explore the role of CD107a in various physiological and pathological conditions.Whether investigating immune responses to infections, cancer, or autoimmune diseases, the PE Anti-Mouse CD107a Antibody (1D4B) provides researchers with a reliable tool to study the function of CD107a in mouse models. Trust Assay Genie for high-quality antibodies that enable cutting-edge research in immunology and beyond.

Product Title:PE Anti-Mouse CD107a Antibody [1D4B]
SKU:AGEL3287
Size:50 Tests, 100 Tests, 200 Tests
Clone No:1D4B
Synonyms:LAMP-1;Lysosome-associated membrane glycoprotein 1; lysosomal membrane glycoprotein 1; CD107 antigen-like family member A; lysosome-associated membrane protein 1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11438
Gene ID:16783
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

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