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Key Features

PE/Cyanine5 Anti-Mouse CD107a Antibody [1D4B] (AGEL3289)

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SKU AGEL3289
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Applications ICFCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, k
Clone 1D4B
Conjugation PE/Cyanine5
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Description

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PE/Cyanine5 Anti-Mouse CD107a Antibody [1D4B]

The PE-Cyanine5 Anti-Mouse CD107a Antibody (1D4B) available at www.assaygenie.com is a highly specific and reliable tool for studying the expression and function of CD107a in mouse samples. CD107a, also known as lysosomal-associated membrane protein-1 (LAMP-1), is a marker of degranulation in NK cells, cytotoxic T cells, and other immune cells.This antibody, produced using advanced technology, offers exceptional sensitivity and specificity for detecting CD107a in flow cytometry and immunofluorescence applications.

It enables researchers to explore cellular degranulation processes, monitor immune cell activation, and investigate cytotoxicity in various experimental contexts.By targeting CD107a, researchers can gain valuable insights into immune responses, especially in the context of host defense, infectious diseases, and cancer immunology. The PE-Cyanine5 Anti-Mouse CD107a Antibody (1D4B) is a valuable tool for advancing our understanding of immune cell function and developing novel therapeutic strategies.

Product Title:PE/Cyanine5 Anti-Mouse CD107a Antibody [1D4B]
SKU:AGEL3289
Size:50 Tests, 100 Tests, 200 Tests
Clone No:1D4B
Synonyms:LAMP-1;Lysosome-associated membrane glycoprotein 1; lysosomal membrane glycoprotein 1; CD107 antigen-like family member A; lysosome-associated membrane protein 1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11438
Gene ID:16783
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

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