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PE/Cyanine7 Anti-Mouse IL-17A Antibody [17F3] (AGEL3105)

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SKU AGEL3105
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications ICFCM
Reactivity Mouse
Host Species Mouse
Isotype Mouse IgG1, κ
Clone 17F3
Conjugation PE/Cyanine7
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Description

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PE/Cyanine7 Anti-Mouse IL-17A Antibody [17F3]

The PE-Cyanine7 Anti-Mouse IL-17A Antibody (17F3) is a cutting-edge tool in immunology research, specifically designed for the detection and analysis of IL-17A, a key cytokine involved in immune responses. This antibody, which has been meticulously validated for use in various applications, is highly selective and exhibits advanced reactivity with mouse samples.IL-17A, a potent pro-inflammatory cytokine, is known for its role in regulating immune responses, particularly in inflammatory and autoimmune conditions. By targeting IL-17A, researchers can gain deeper insights into the mechanisms underlying immune-mediated diseases, paving the way for novel therapeutic interventions.

The PE-Cyanine7 Anti-Mouse IL-17A Antibody (17F3) enables precise detection of IL-17A in various experimental settings, making it an indispensable tool for studies focusing on immunology, inflammation, and autoimmune disorders. Its exceptional specificity and sensitivity ensure accurate and reliable results, facilitating groundbreaking discoveries in the field of immune modulation and therapeutic development.

Product Title:PE/Cyanine7 Anti-Mouse IL-17A Antibody [17F3]
SKU:AGEL3105
Size:50 Tests, 100 Tests, 200 Tests
Clone No:17F3
Synonyms:Interleukin-17A;Il17a;Ctla8;
Host Species:Mouse
Reactivity:Mouse
Application:ICFCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62386
Gene ID:16171
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-25A in vivo.

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