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PE/GenieFluor 594 Anti-Mouse CD3 Antibody [17A2] (AGEL3184)

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SKU AGEL3184
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, k
Clone 17A2
Conjugation PE/AF594
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Description

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PE/GenieFluor 594 Anti-Mouse CD3 Antibody [17A2]

The PE GenieFluor® 594 Anti-Mouse CD3 Antibody (17A2) (AG-EL3184) offered by Assay Genie is a valuable tool for immunological research involving mouse models. This antibody specifically targets the CD3 antigen, a key component of the T-cell receptor complex essential for T-cell activation and function. Developed for use in flow cytometry applications, the PE-conjugated antibody enables precise detection and analysis of CD3-expressing T cells in various tissues and cell populations. Its high specificity and sensitivity make it an ideal choice for investigating T-cell responses, immune cell differentiation, and monitoring immune system dynamics in experimental settings.By targeting CD3, this antibody facilitates the exploration of T-cell-mediated immune responses, including T-cell activation, proliferation, and cytokine production.

Its application in immunology research, particularly in studies related to autoimmune diseases, infectious diseases, and cancer immunotherapy, offers valuable insights into the intricate mechanisms of T-cell function and regulation.Overall, the PE GenieFluor® 594 Anti-Mouse CD3 Antibody (17A2) is a reliable tool for researchers seeking to deepen their understanding of T-cell biology and immune system function in mouse models, with potential implications for the development of novel immunotherapeutic strategies.

Product Title:PE/GenieFluor 594 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL3184
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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