The PRPH Antibody (CAB4048) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using a polyclonal antibody design, exhibits high reactivity with human samples and is validated for use in various applications including Western blot and immunohistochemistry.Peripherin is known to play a critical role in the formation and maintenance of neuronal cytoskeleton, particularly in peripheral sensory neurons. Its expression has been linked to various neurological disorders and nerve injury, making it an important target for studies in neuroscience and neurology.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PRPH Antibody
SKU:
CAB4048
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.
Purification Method
Affinity purification
Gene ID
5630
RRID
AB_2765469
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PRPH Rabbit pAb (CAB4048) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Immunofluorescence analysis of Neuro-2a cells using PRPH Rabbit pAb (CAB4048) at dilution of 1:20 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.