The GSK-3 Rabbit Polyclonal Antibody is a vital tool for researchers studying glycogen synthase kinase-3 (GSK-3), a key enzyme involved in numerous signaling pathways and cellular processes. This high-quality antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with GSK-3 in human samples.GSK-3 is known to play a crucial role in various biological processes, including cell growth, differentiation, and apoptosis. Dysregulation of GSK-3 activity has been implicated in a variety of diseases, including cancer, diabetes, and neurodegenerative disorders.
By targeting GSK-3 with this antibody, researchers can gain valuable insights into the function and regulation of this important enzyme in both normal and disease states.With its specificity and reliability in detecting GSK-3, the GSK-3 Rabbit Polyclonal Antibody is an essential tool for scientists conducting research in cell biology, molecular biology, and drug development. Its versatility in various cell types and tissues makes it a valuable asset in advancing our understanding of GSK-3 and its implications in health and disease.
Product Name:
GSK-3α/β Polyclonal Antibody
SKU:
CAB21167
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 253-368 of human GSK-3α/β (NP_063937.2).
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2931/ 2932
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using GSK-3α/β Rabbit pAb (CAB21167) at dilution of 1:20 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
