The MARK2 Antibody (CAB16706) is a high-quality antibody developed for reliable detection and analysis of target proteins. This high-quality antibody, produced in rabbits, offers strong reactivity with human samples and has been validated for use in Western blot applications.Mark2, also known as MARK2 or MAP/microtubule affinity-regulating kinase 2, is involved in various cellular processes such as cell polarity, cell migration, and cytoskeletal organization. Dysregulation of Mark2 has been associated with diseases such as cancer, neurodegenerative disorders, and metabolic diseases, highlighting its importance in biological processes.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MARK2 Antibody
SKU:
CAB16706
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
2011
RRID
AB_2770293
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MARK2 Rabbit pAb (CAB16706) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Immunofluorescence analysis of L929 cells using MARK2 Rabbit pAb (CAB16706) at dilution of 1:100. Blue: DAPI for nuclear staining.
