The Phospho-MYL12A (S18) Polyclonal Antibody (CABP0412) is a valuable tool for researchers studying MYL12A phosphorylation, a key event in the regulation of cell migration and contractility. This antibody, produced in rabbits, specifically targets the phosphorylated form of MYL12A at serine 18, allowing for precise detection and analysis in Western blot experiments. Its high reactivity with human samples makes it a reliable choice for investigating the role of MYL12A phosphorylation in various cellular processes.MYL12A, a myosin regulatory light chain, plays a crucial role in the regulation of actomyosin contraction and cell motility. Phosphorylation of MYL12A at serine 18 is known to enhance its interaction with actin filaments, leading to increased cell contractility and migration.
This antibody provides researchers with a powerful tool to study the impact of MYL12A phosphorylation on cell behavior, making it ideal for studies in cell biology, cancer metastasis, and tissue remodeling.Understanding the molecular mechanisms underlying MYL12A phosphorylation is essential for unraveling its functional significance in various physiological and pathological conditions. The Phospho-MYL12A (S18) Polyclonal Antibody (CABP0412) offers researchers a reliable and specific tool to explore the complex interplay between MYL12A phosphorylation and cellular processes, paving the way for innovative discoveries
Product Name:
Phospho-MYL12A-S18 Rabbit Polyclonal Antibody
SKU:
CABP0412
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A phospho specific peptide corresponding to residues surrounding S18 of human MYL12A
This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
Purification Method:
Affinity purification
Gene ID:
10627
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293 cells untreated or treated with starvation using Phospho-MYL12A-S18 Rabbit pAb (CABP0412).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
