The RIPK2 Antibody (CAB2498) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.RIPK2 is a crucial signaling molecule involved in the activation of NF-κB and MAPK pathways following microbial infection, making it a critical target for research in immunology and infectious diseases. By binding to RIPK2, this antibody enables the detection and analysis of RIPK2 protein levels in various cell types, allowing for in-depth studies on the role of RIPK2 in immune signaling pathways.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
RIPK2 Antibody
SKU:
CAB2498
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CCK, RICK, RIP2, CARD3, GIG30, CARDIAK, RIPK2
Positive Sample:
Mouse lung, Mouse brain, Rat brain
Cellular Localization:
Cytoplasm.
Calculated MW:
61kDa
Observed MW:
61kDa
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Purification Method
Affinity purification
Gene ID
8767
RRID
AB_2764389
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using RIPK2 Rabbit pAb (CAB2498) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
