The Polr3A Polyclonal Antibody (CAB10737) is a valuable tool for researchers studying RNA polymerase III subunit A (Polr3A), a key enzyme involved in the transcription of various RNA molecules. This antibody, produced in rabbits, offers high specificity and reactivity with human samples, making it ideal for use in a variety of research applications, including Western blotting.Polr3A plays a crucial role in RNA synthesis, particularly in the production of small non-coding RNAs that serve important regulatory functions in gene expression.
Dysregulation of Polr3A has been implicated in various diseases, including cancer and neurological disorders, making it a promising target for further investigation.By using the Polr3A Polyclonal Antibody, researchers can effectively detect and analyze Polr3A protein levels in different cell types and tissues, allowing for a better understanding of its role in transcriptional regulation and disease development. This antibody is a valuable tool for advancing research in genetics, oncology, and molecular biology.
Product Name:
POLR3A Rabbit Polyclonal Antibody
SKU:
CAB10737
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human POLR3A (NP_008986.2).
The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response.
Purification Method:
Affinity purification
Gene ID:
11128
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using POLR3A Rabbit pAb (CAB10737) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
