The POU3F3 Polyclonal Antibody (PAC013570) is a valuable tool for researchers studying the POU3F3 protein, a transcription factor known to be involved in neurological development and function. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to POU3F3, researchers can detect and analyze this important protein in various cell types, making it suitable for studies in neurobiology and developmental biology.POU3F3, also known as Brain-1, plays a crucial role in the regulation of neuronal gene expression and differentiation.
Its function in the nervous system makes it a prime target for research into neurological disorders, neurodevelopmental diseases, and brain development. Understanding the role of POU3F3 is essential for uncovering its potential as a therapeutic target for various neurological conditions.Overall, the POU3F3 Polyclonal Antibody is a reliable resource for researchers looking to investigate the role of POU3F3 in neurological development and function, and its implications in neurological diseases. Its specificity and reactivity make it a valuable tool for advancing research in the field of neuroscience.
Oct8: Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met- mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3'). Belongs to the POU transcription factor family. Class- 3 subfamily.Protein type: DNA-binding; Transcription factorChromosomal Location of Human Ortholog: 2q12.1Cellular Component: nucleusMolecular Function: sequence-specific DNA bindingBiological Process: central nervous system development; negative regulation of apoptosis; negative regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]
