The PRMT6 Rabbit Monoclonal Antibody (CAB5085) is a cutting-edge tool for researchers studying protein arginine methyltransferase 6 (PRMT6), a key enzyme involved in epigenetic regulation and cellular processes. This antibody, developed specifically for the detection of PRMT6 in human samples, is highly sensitive and specific, making it an invaluable asset for experiments such as Western blotting.PRMT6 is known to play a critical role in gene expression, chromatin remodeling, and cell differentiation, making it a promising target for research in various fields, including cancer biology, neurobiology, and developmental biology.
By using the PRMT6 Rabbit Monoclonal Antibody, researchers can accurately analyze PRMT6 expression levels and understand its function in different cell types and tissues.By utilizing this antibody, scientists can gain valuable insights into the role of PRMT6 in disease progression and potential therapeutic interventions. Its high specificity and reliability make it an essential tool for advancing our understanding of epigenetic regulation and its implications in various diseases.
Product Name:
PRMT6 Rabbit Monoclonal Antibody
SKU:
CAB5085
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PRMT6 (Q96LA8).
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Purification Method:
Affinity purification
Gene ID:
55170
Clone Number:
ARC1277
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRMT6 Rabbit mAb (CAB5085) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
