The PTGDR Polyclonal Antibody (CAB12877) is a specialized tool for researchers studying PTGDR, a protein involved in the inflammatory response and immune regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications. By binding to the PTGDR protein, this antibody allows for the detection and analysis of PTGDR in various cell types, making it a valuable asset for studies in immunology, allergy research, and inflammatory conditions.
PTGDR, also known as prostaglandin D2 receptor 1, plays a crucial role in mediating inflammation and immune responses. By understanding the functions of PTGDR, researchers can gain insights into the mechanisms underlying inflammatory diseases, such as asthma, allergic reactions, and autoimmune disorders. The PTGDR Polyclonal Antibody is an essential tool for studying the role of PTGDR in these contexts and for developing potential therapeutic strategies targeting this protein.
Product Name:
PTGDR Rabbit Polyclonal Antibody
SKU:
CAB12877
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-359 of human PTGDR (NP_000944.1).
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from NIH/3T3 cells, using PTGDR Rabbit pAb (CAB12877) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
