The P23/PTGES3 Antibody (CAB5325) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.PTGES3 is an enzyme involved in the production of prostaglandin E2 (PGE2), a key mediator of inflammation and pain. The ability to detect and quantify PTGES3 protein levels in various cell types is essential for understanding its role in inflammatory responses and developing targeted therapies for conditions such as arthritis, cancer, and fibrosis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
P23/PTGES3 Antibody
SKU:
CAB5325
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
P23, TEBP, cPGES, P23/PTGES3
Positive Sample:
HeLa, Jurkat, Mouse testis, Rat testis
Cellular Localization:
Cytoplasm.
Calculated MW:
19kDa
Observed MW:
23kDa
This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes.
Purification Method
Affinity purification
Gene ID
10728
RRID
AB_2766137
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using P23/PTGES3 Rabbit pAb (CAB5325) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
