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Purified Anti-Mouse IL-17A Antibody [17F3] (AGEL3512)

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SKU AGEL3512
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications ICFCM
Reactivity Mouse
Host Species Mouse
Isotype Mouse IgG1, k
Clone 17F3
Conjugation Unconjugated
€25 - €63
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Description

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Purified Anti-Mouse IL-17A Antibody [17F3]

The Purified Anti-Mouse IL-17A Antibody (17F3) is a key tool for researchers studying immune response in mice. This antibody, generated against IL-17A, a cytokine involved in inflammatory processes and immune regulation, is highly specific and ideal for use in various applications such as ELISA and immunohistochemistry. By targeting IL-17A, researchers can gain insight into the role of this cytokine in immune-mediated diseases such as autoimmune disorders, inflammatory conditions, and cancer.

With its high reactivity and specificity for mouse samples, the Purified Anti-Mouse IL-17A Antibody (17F3) is a valuable asset for studies in immunology and disease research.

Product Title:Purified Anti-Mouse IL-17A Antibody [17F3]
SKU:AGEL3512
Size:25µg, 100µg
Clone No:17F3
Synonyms:Interleukin-17A;Il17a;Ctla9;
Host Species:Mouse
Reactivity:Mouse
Application:ICFCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:Q62386
Gene ID:16171
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A in vivo.

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