The RAB4A Monoclonal Antibody (CAB3979) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit monoclonal technology, demonstrates high specificity and sensitivity in detecting Rab4a in various cell types.Rab4a is involved in the recycling of endocytosed receptors and plays a critical role in controlling the endocytic pathway. Dysregulation of Rab4a has been linked to various diseases, including cancer and neurodegenerative disorders. By targeting Rab4a with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
RAB4A Monoclonal Antibody
SKU:
CAB3979
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC2607
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.
Purification Method
Affinity purification
Gene ID
5867
RRID
AB_2863168
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using RAB4A Rabbit mAb (CAB3979) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.