The RABL2A Polyclonal Antibody (PACO06786) is a valuable tool for research involving RABL2A, a protein known for its role in cell division and intracellular transport processes. This antibody, produced in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot applications. By targeting the RABL2A protein, this antibody enables the detection and analysis of RABL2A in various cell types, making it an ideal choice for studies in cell biology and molecular biology research.
RABL2A is a key player in cellular processes such as mitosis, cytokinesis, and vesicle trafficking, making it essential for maintaining proper cell function and division. Understanding the function and regulation of RABL2A is crucial for unraveling its contribution to diseases like cancer, neurodegenerative disorders, and developmental anomalies. By studying RABL2A, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
Antibody Name:
RABL2A Antibody (PACO06786)
Antibody SKU:
PACO06786
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:20000, WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the C-terminal region of human Rab L2A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of Jurkat cells using Rab L2A Polyclonal Antibody.
Western Blot analysis of COLO205 cells using Rab L2A Polyclonal Antibody.
Synonyms:
RABL2A; Rab-like protein 2A
UniProt Protein Function:
RABL2A: a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Two alternatively spliced transcript variants have been identified, both encoding the same protein. [provided by RefSeq, Jul 2008]Protein type: G protein, monomeric, Rab; G protein; G protein, monomericChromosomal Location of Human Ortholog: 2q13Cellular Component: intracellularMolecular Function: GTP binding; GTPase activity; protein bindingBiological Process: small GTPase mediated signal transduction
UniProt Protein Details:
NCBI Summary:
This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
