The RASSF9 Polyclonal Antibody (PAC016949) is a valuable tool for researchers studying the role of RASSF9, a member of the Ras association domain family, in cellular processes and signaling pathways. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and is validated for use in Western blot applications. By binding to the RASSF9 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it suitable for investigations in the fields of cell biology and cancer research.
RASSF9 is known to be involved in important cellular functions such as cell cycle regulation, apoptosis, and cell proliferation. Its dysregulation has been linked to the development and progression of various cancers, making it a promising target for therapeutic interventions. By studying the role of RASSF9 using this polyclonal antibody, researchers can gain insights into its molecular mechanisms and potential implications in disease pathology, paving the way for innovative treatments and drug discovery efforts.
Antibody Name:
RASSF9 Antibody (PACO16949)
Antibody SKU:
PACO16949
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human RASSF9
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO16949(RASSF9 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16949(RASSF9 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The protein encoded by this gene localizes to perinuclear endosomes. This protein associates with peptidylglycine alpha-amidating monooxygenase, and may be involved with the trafficking of this enzyme through secretory or endosomal pathways.
Synonyms:
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
UniProt Protein Function:
RASSF9: May play a role in regulating vesicuar trafficking in cells.Chromosomal Location of Human Ortholog: 12q21.31Cellular Component: trans-Golgi network transport vesicle membrane; cytosol; endosomeMolecular Function: protein binding; transporter activityBiological Process: signal transduction; endosome transport; protein targeting
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene localizes to perinuclear endosomes. This protein associates with peptidylglycine alpha-amidating monooxygenase, and may be involved with the trafficking of this enzyme through secretory or endosomal pathways. [provided by RefSeq, Jul 2008]
