The RCL1 Polyclonal Antibody (CAB4382) is a valuable tool for researchers studying RCL1, a key protein involved in RNA processing and gene expression regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the RCL1 protein, this antibody enables researchers to detect and analyze RCL1 levels in various cell types, making it essential for studies in molecular biology and gene regulation.RCL1, also known as RNA 3'-terminal phosphate cyclase, plays a crucial role in RNA metabolism by catalyzing the formation of RNA 3'-5'-cyclic phosphate ends.
Dysregulation of RCL1 has been implicated in various disease states, including cancer and neurodegenerative disorders. By understanding the function of RCL1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets for intervention. The RCL1 Polyclonal Antibody is a valuable tool for exploring the role of RCL1 in health and disease, making it an essential reagent for cutting-edge research in molecular biology.
Product Name:
RCL1 Rabbit Polyclonal Antibody
SKU:
CAB4382
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RCL1 (NP_005763.3).
Predicted to enable endoribonuclease activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be active in nucleolus.
Purification Method:
Affinity purification
Gene ID:
10171
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RCL1 Rabbit pAb (CAB4382) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
