Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence; a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B; it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system; predominantly monocytes; macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family; Cathepsin Z may be involved in tumorigenesis.
Product Name:
Human Cathepsin Z Recombinant Protein (RPES4454)
Product Code:
RPES4454
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ
Accession:
Q9UBR2
Sequence:
Gly24-Val303
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
32.5 kDa
AP Mol Mass:
37 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM HAc-NaAc; 150mM NaCl; pH 4.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
