Low affinity immunoglobulin gamma Fc region receptor III-B; also known as Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b and FCGR3B. The molecule FCGR3B belongs to the GPI-anchor membrane protein family and comprises two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. The FCGR3B gene, which resides in the FCGR gene cluster and is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation, localizes. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. Human CD16b/FCGR3B Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human CD16b/FCGR3B Recombinant Protein (RPES0557)
Product Code:
RPES0557
Size:
50µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR6B,FCRIII,FCRIIIb
Accession:
O75015-1
Sequence:
Met 18-Gly 193
Fusion tag:
Activity:
Measured by its ability to bind human IgG1 in a functional ELISA.2. Labeling ratio of biotin to protein: 5.51.
Endotoxin:
Please contact us for more information.
Protein Construction:
A DNA sequence encoding the mature form of human CD16b (O75015-1) (Met 18-Gly 193) was expressed and purified. The expressed protein was biotinylated in vitro.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
20 kDa
Formulation:
Lyophilized from sterile PBS; pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
