Description
| Product Name: | Recombinant Human ECF/CCL11 Protein (Sumo Tag) |
| SKU: | RPES8052 |
| Size: | 20μg |
| Tag: | N-Sumo |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | P51671 |
| Sequence: | Gly24-Pro97 |
| Calculated Molecular Weight: | 24.1 kDa |
| Observed Molecular Weight: | 28 kDa |
| Synonyms: | C-C motif chemokine 11, CCL 11, CCL11, CCL11, chemokine (C-C motif) ligand 11, Chemokine C C motif ligand 11, Chemokine CC Motif Ligand 11, Chemokine ligand 11, Eosinophil chemotactic protein, Eotaxin, eotaxin-1, MGC22554, SCYA 11, SCYA11, Small inducible cytokine A11, Small inducible cytokine subfamily A (Cys Cys) member 11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin), Small inducible cytokine subfamily A member 11, Small-inducible cytokine A11 |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
