Erythropoietin (Epo); a glycoprotein produced primarily by the kidney; is the principal factor that regulates erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells. The biological effects of Epo are mediated by the erythropoietin receptor (Epo R). The presence of a soluble form of the Epo R has also been detected on human sera. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.
Product Name:
Human Erythropoietin R/EPOR Recombinant Protein (RPES2877)
Recombinant Human Erythropoietin R is produced by our Mammalian expression system and the target gene encoding Ala25-Pro250 is expressed with a Fc tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
54.5 kDa
AP Mol Mass:
55-75 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS;pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
