Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus; a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose; which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II; an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.
Product Name:
Human GALK1/Galactokinase Recombinant Protein (RPES2611)
Product Code:
RPES2611
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Galactokinase, Galactose Kinase, GALK1, GALK
Accession:
P51570
Sequence:
Met1-Leu392
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human GALK1 is produced by our E.coli expression system and the target gene encoding Met1-Leu392 is expressed with a 6His tag at the C-terminus.
Purity:
> 85% as determined by reducing SDS-PAGE.
Mol Mass:
43.3 kDa
AP Mol Mass:
45 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
