Granoclin (GCA) is a cytoplasmic granule membrane protein with four EF-hand domains. Calcium-binding protein GCA is abundant in human neutrophils. GCA is widely expressed in bone marrow and can be found in neutrophils and macrophages. Calcium-binding protein GCA works with SRI and LCP1 to promote neutrophil adhesion to fibronectin. GCA also may play a role in the formation of focal adhesions. Human Grancalcin/GCA Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Grancalcin/GCA Recombinant Protein (RPES5224)
Product Code:
RPES5224
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Grancalcin, GCA, GCL
Accession:
P28676
Sequence:
Met 1-Ile217
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Grancalcin is produced by our E.coli expression system and the target gene encoding Met1-Ile217 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
24.0 kDa
AP Mol Mass:
26 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; 1mM EDTA; pH 8.5.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
