Interferon-gamma (IFN-gamma) is the most potent interferon produced by mitogenically or antigenically activated lymphocytes. It is structurally distinct from type I interferon and has a greater immunoregulatory role. It's been linked to class II histocompatibility antigens being expressed in cells that don't normally produce them, resulting in autoimmune disease.Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens; mitogens; or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. The formation of IFN-gamma is induced by IL-2, FGF-basic, and EGF. Human Interferon gamma/IFNG Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Interferon gamma/IFNG Recombinant Protein (RPES1899)
Recombinant Human Interferon gamma is produced by our E.coli expression system and the target gene encoding Gln24-Gln166 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
16.9 kDa
AP Mol Mass:
16 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
