Description
Recombinant Human PDGF-AA Protein
The Recombinant Human PDGF-AA Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating PDGF-AA function and its implications in health and disease.
This product (SKU: RPCB1346) is produced using advanced expression systems and features a No-tag tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 14.31 kDa with an observed molecular weight of 20 kDa kDa under denaturing conditions, achieving ≥ 90% as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography | |
Mammalian & Bacterial Expression Systems | |
High lot-to-lot consistency via strict QC |
Product Name: | Recombinant Human PDGF-AA Protein |
SKU: | RPCB1346 |
Size: | 10 μg , 20 μg , 50 μg , 100 μg |
Reactivity: | Human |
Synonyms: | PDGF1, PDGF-A |
Tag: | No-tag |
Calculated MW: | 14.31 kDa |
Observed MW: | 20 kDa kDa |
Gene ID: | 5154 |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human PDGF-AA Protein (RPCB1346), tested reactivity in Pichia and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 0.1 EU/μg of the protein by LAL method. |
Purity: | ≥ 90% as determined by SDS-PAGE. |
Formulation: | Lyophilized from a 0.22 μm filtered solution of 20 mM NaAc,pH 4.5 |
Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.