PIGR belongs to the immunoglobulin superfamily and binds polymeric immunoglobulins on the basolateral surface of epithelial cells. Immune globulin A nephropathy is caused by several PIGR variants. Protein-energy malnutrition and periampullary adenocarcinoma are two examples of diseases linked to PIGR. The innate immune system and the integrated breast cancer pathway are two pathways linked to PIGR. Human PIGR Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Recombinant Human Polymeric immunoglobulin receptor is produced by our Mammalian expression system and the target gene encoding Lys19-Arg638 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
95.0 kDa
AP Mol Mass:
120 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM Tris,150mM NaCl,pH 8.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
