RBP4 (Retinol Binding Protein 4) is a lipocalin that also shows up in the blood. RBP4 is the specific vector for retinol. Adipose tissue expresses and secretes RBP4, which is associated with insulin resistance. Retinol is delivered from the liver to the peripheral tissues by retinoic acid receptor-bound protein 4 (RBP4). The RBP-retinol complex binds to transthyretin in the plasma, preventing its filtration via the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems. Human RBP4 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human RBP4 Recombinant Protein (RPES4073)
Product Code:
RPES4073
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
RDCCAS,Retinol-Binding Protein 4, Plasma Retinol-Binding Protein, PRBP, RBP, RBP4
Accession:
NP_006735.2
Sequence:
Glu19-Leu201
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Retinol-Binding Protein 4 is produced by our E.coli expression system and the target gene encoding Glu19-Leu201 is expressed.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
21.2 kDa
AP Mol Mass:
20 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 50mM TrisHCl; 10mM CaCl2; 150mM NaCl; pH 7.5 .
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
