Reticulocalbin-3 is a member of the CREC family that is involved in the secretory pathway. Members of the CREC family consist of a number of multiple EF-hand domains. Reticulocalbin-3 localizes to the endoplasmic reticulum lumen. The bioinformaticanalysis of Reticulocalbin-3 reveal that it is a putative Ca2+-binding protein. In addition; it has been shown that autoactivation and secretion of PACE4 was increased upon co-expression with Reticulocalbin-3. The proPACE4-RCN-3 complex is plays an important role in the biosynthesis of PACE4.
Product Name:
Human Reticulocalbin 3/RCN3 Recombinant Protein (RPES1337)
Product Code:
RPES1337
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Reticulocalbin-3, EF-Hand Calcium-Binding Protein RLP49, RCN3
Accession:
Q96D15
Sequence:
Lys21-Leu328
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Reticulocalbin-3 is produced by our Mammalian expression system and the target gene encoding Lys21-Leu328 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
36.2 kDa
AP Mol Mass:
43 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM TrisHCl;150mM NaCl;1mM DTT;10%Glycerol;pH7.4.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
