emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent; inhibiting axonal outgrowth; or as a chemoattractive agent; stimulating the growth of apical dendrites. In both cases; the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.
Product Name:
Human Semaphorin 3A/SEMA3A Recombinant Protein (RPES5094)
Product Code:
RPES5094
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Semaphorin III, SEMA3A, SEMAD, Hsema-I, SEMA1, SemD, Semad, coll-1 , Hsema-III, Sema III
Accession:
Q14563
Sequence:
Lys26-Phe546
Fusion tag:
N-His-Flag
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Semaphorin 3A is produced by our Mammalian expression system and the target gene encoding Lys26-Phe546 is expressed with a 6His-Flag tag at the C-terminus.
Purity:
> 90% as determined by reducing SDS-PAGE.
Mol Mass:
61.3 kDa
AP Mol Mass:
70-75 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
