Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. STAT1 can also form a homodimer termed IFN-gamma-activated factor (GAF) through tyrosine and serine phosphorylation; migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes; resulting in an antiviral cellular state. STAT1 is a transcription activator and signal transducer that regulates cellular responses to interferons. The cause of STAT1 deficiency total and familial candidiasis type 7 is a lack of the enzyme STAT1. Human STAT1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human STAT1 Recombinant Protein (RPES1886)
Product Code:
RPES1886
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Signal Transducer and Activator of Transcription 1-Alpha/Beta, Transcription Factor ISGF-3 Components p91/p84, STAT1, CANDF7,IMD31A,IMD31B,IMD31C,ISGF-3,STAT91
Accession:
P42224-2
Sequence:
Met 1-Val712
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Signal Transducer and Activator of Transcription 1 is produced by our E.coli expression system and the target gene encoding Met1-Val712 is expressed.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
83.3 kDa
AP Mol Mass:
85 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
