Syndecan-1 is a single-pass type I membrane protein that belongs to the syndecan proteoglycan family. The syndecans mediate cell binding; cell signaling; and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. Human SDC1 is synthesized as a 310 amino acid precursor that contains a 22 amino acid signal sequence; and a 288 amino acid mature chain. The Syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation; cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered Syndecan-1 expression has been detected in several different tumor types.
Product Name:
Human Syndecan/SDC1 Recombinant Protein (RPES4664)
Product Code:
RPES4664
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Syndecan-1, SYND1, CD138, SDC1, SDC
Accession:
P18827
Sequence:
Gln18-Glu251(Leu136Gln)
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Syndecan-1 is produced by our Mammalian expression system and the target gene encoding Gln18-Glu251(Leu136Gln) is expressed with a Fc tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
51 kDa
AP Mol Mass:
80-90 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4 .
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
