Tumor associated calcium signal transducer 2 (TACSTD2; TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Product Name:
Human TROP2/TACSTD2 Recombinant Protein (RPES3941)
Recombinant Human TROP2 is produced by our Mammalian expression system and the target gene encoding Thr88-Thr274 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
22.6 kDa
AP Mol Mass:
28-40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; 5%Trehalose; 2mM EDTA ; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
