The Recombinant Mouse Alpha-Synuclein/SNCA Protein is a high-quality recombinant protein designed for murine biological research applications. This protein serves as an essential reagent in mouse model studies, comparative immunology research, and preclinical therapeutic evaluations, enabling scientists to investigate Alpha-Synuclein/SNCA biology and its relevance to human disease mechanisms through translational research approaches.
This product (SKU: RPCB0666) is produced using E. coli and features a No tag tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 14.49 kDa with an observed molecular weight of 16-20 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography
Mammalian & Bacterial Expression Systems
High lot-to-lot consistency via strict QC
Product Name:
Recombinant Mouse Alpha-Synuclein/SNCA Protein
SKU:
RPCB0666
Size:
10 μg , 20 μg , 50 μg , 100 μg
Reactivity:
Mouse
Synonyms:
Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloidprecursor, NACP, Snca
High quality, high purity and low endotoxin recombinant Recombinant Mouse Alpha-Synuclein/SNCA Protein (RPCB0666), tested reactivity in E. coli and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:
< 1 EU/μg of the protein by LAL method.
Purity:
≥ 95 % as determined by SDS-PAGE.
Formulation:
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.Contact us for customized product form or formulation.
Reconstitution:
Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Storage:
Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but alsoexpressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D andhistones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatorycomponent of vesicular transport in neuronal cells. It has been suggested that SNCA is related to thepathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to DementiaLewy Body (DLB).
Recombinant Mouse Alpha-Synuclein/SNCA Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
