Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
Product Name:
Mouse CD74 Recombinant Protein (RPES1010)
Product Code:
RPES1010
Size:
10µg
Species:
Mouse
Expressed Host:
Human Cells
Synonyms:
Cluster of Differentiation 74,CD74 antigen, CD74 molecule, major histocompatibility complex, class II invariant chain, DHLAG gamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, MHC HLA-DR gamma chain, CD74, DHLAG, HLADG, Ia-gamma, INVG34,
Accession:
P04441-2
Sequence:
Gln56-Leu215
Fusion tag:
C-mFc-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse HLA class II histocompatibility antigen gamma chain is produced by our Mammalian expression system and the target gene encoding Gln56-Leu215 is expressed with a mFc, 6His tag at the C-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
44.5 kDa
AP Mol Mass:
45-55 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
