Description
Recombinant Mouse Fc-gamma RIV/FCGR3A/CD16a Protein
The Recombinant Mouse Fc-gamma RIV/FCGR3A/CD16a Protein is a high-quality recombinant protein designed for murine biological research applications. This protein serves as an essential reagent in mouse model studies, comparative immunology research, and preclinical therapeutic evaluations, enabling scientists to investigate Fc-gamma RIV/FCGR3A/CD16a biology and its relevance to human disease mechanisms through translational research approaches.
This product (SKU: RPCB0909) is produced using HEK293 cells and features a C-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 21.77 kDa with an observed molecular weight of 32-38 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography | |
Mammalian & Bacterial Expression Systems | |
High lot-to-lot consistency via strict QC |
Product Name: | Recombinant Mouse Fc-gamma RIV/FCGR3A/CD16a Protein |
SKU: | RPCB0909 |
Size: | 10 μg , 20 μg , 50 μg , 100 μg |
Reactivity: | Mouse |
Synonyms: | Fc gamma RIV, CD16-2, Fcgr4, FCGR4, mouse igg, FcgR4 |
Tag: | C-His |
Expression Host: | HEK293 cells |
Calculated MW: | 21.77 kDa |
Observed MW: | 32-38 kDa |
Gene ID: | 246256 |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse Fc-gamma RIV/FCGR3A/CD16a Protein (RPCB0909), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 0.1 EU/μg of the protein by LAL method. |
Purity: | ≥ 95 % as determined by SDS-PAGE. |
Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
FcgammaRIV is a relatively new IgG Fc receptor (FcgammaR) that is reported to contribute to the pathogenesis of autoimmune diseases.FcgammaRIII and FcgammaRIV are each essential to trigger an FcRgamma-linker for activation of T-cell-dependent signal that drives C5a production in the Arthus reaction. A combined requirement for FcgammaRIII and FcgammaRIV in autoimmune injury, and identify the linker for activation of T cells adaptor as an integral component of linked FcgammaR and C5a anaphylatoxin receptor activation to generate inflammation.