Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin ?4β1.
Product Name:
Mouse Galectin 9/LGALS9 Recombinant Protein (RPES1711)
Product Code:
RPES1711
Size:
10µg
Species:
Mouse
Expressed Host:
E.coli
Synonyms:
Galectin-9, Lgals9, Gal-9
Accession:
O08573-2
Sequence:
Met1-Thr322
Fusion tag:
N-GST
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Mouse Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus.
Purity:
> 90% as determined by reducing SDS-PAGE.
Mol Mass:
62.8 kDa
AP Mol Mass:
58 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM PB, 1mM EDTA, 5mM p-ME, 5%Trehalose, 400mM Nacl, pH6.5
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
