Description
Recombinant Mouse PDGF-AA Protein
The Recombinant Mouse PDGF-AA Protein is a high-quality recombinant protein designed for murine biological research applications. This protein serves as an essential reagent in mouse model studies, comparative immunology research, and preclinical therapeutic evaluations, enabling scientists to investigate PDGF-AA biology and its relevance to human disease mechanisms through translational research approaches.
This product (SKU: RPCB2195) is produced using Pichia and features a N-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 14.5 kDa. with an observed molecular weight of 20&26 KDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography | |
Mammalian & Bacterial Expression Systems | |
High lot-to-lot consistency via strict QC |
Product Name: | Recombinant Mouse PDGF-AA Protein |
SKU: | RPCB2195 |
Size: | 50 μg |
Reactivity: | Mouse |
Synonyms: | PDGF1, PDGF-A, PDGFA |
Tag: | N-His |
Expression Host: | Pichia |
Calculated MW: | 14.5 kDa. |
Observed MW: | 20&26 KDa |
Gene ID: | 18590 |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse PDGF-AA Protein (RPCB2195), tested reactivity in Pichia and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | Please contact us for more information. |
Purity: | ≥ 95 % as determined by SDS-PAGE. |
Formulation: | Lyophilized from a 0.22 μm filtered solution of 0.1% TFA, 30% CAN. Contact us for customized product form or formulation. |
Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.